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The Cancer Letter Inc.
PO Box 9905
DC 20016
Tel: 202-362-1809
Fax: 202-379-1787
publication date: Nov 30, 2015
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Researchers: All Pediatric Patients, Regardless of Family History, Could Benefit from Genomic Screening


According to investigators at St. Jude Children’s Research Hospital, comprehensive genomic screening may be warranted for all pediatric cancer patients, not just those with a family history of cancer, based on a detailed analysis of the role of germline mutations in genes associated with cancer predisposition.

Ultimately, researchers anticipate that systematic monitoring of patients and family members who have germline mutations in cancer predisposition genes will allow the detection of cancers at their earliest and most curable stage.

The study from the St. Jude and the Washington University Pediatric Cancer Genome Project was published in the New England Journal of Medicine.

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