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The Cancer Letter Inc.
PO Box 9905
DC 20016
Tel: 202-362-1809
Fax: 202-379-1787
publication date: Nov 3, 2015
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NCI CTEP-Approved Trials for the Month of October


The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.


Pilot Phase

9664: Pilot Study for the Treatment of Steroid-Refractory Sclerodermatous Chronic Graft-Versus-Host Disease (GVHD) with GDC-0449 (GDC-0449). Huntsman Cancer Institute/University of Utah; Kovacsovics, Tibor J. (503) 494-1877


Phase II

9855: A Phase 2 Study of CDX-011 (Glembatumumab Vedotin) for Metastatic Uveal Melanoma. University of Texas M D Anderson Cancer Center P2C; Patel, Sapna Pradyuman. (713) 792-2921


9880: A Phase 2 Study of Subcutaneous Recombinant Human IL-15 and Haploidentical Donor Natural Killer Cell Infusion in Adults with Refractory or Relapsed Acute Myelogenous Leukemia. University of Minnesota/Masonic Cancer Center; Miller, Jeffrey Steven. (612) 624-0123


S1505: A Randomized Phase II Study of Perioperative mFOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma. SWOG; Sohal, Davendra Pratap Singh. (216) 444-8258


Phase II/III

NRG-CC003: Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer. NRG Oncology; Gondi, Vinai. (630) 352-5350


Other Phases

AAML14B8-Q: Minimal Residual Disease Surveillance of Pediatric Normal Karyotype AML Via Error-Corrected Next-Generation Sequencing. Children’s Oncology Group; Druley, Todd E. (314) 286-2124


AAML15B4-Q: Tumor Immunity in Children with Cancer. Children’s Oncology Group; Dhodapkar, Kavita M. (203) 785-4640


AMC-S004: Clinical and Genomic Factors for Prognosis of AIDS Primary Effusion Lymphoma. AIDS Malignancy Consortium; Reid, Erin Gourley. (858) 822-6276


AOST15B1-Q: Descriptive Study of Genome-Wide DNA Methylation Patterns in Osteosarcoma Tissues and Their Potential Role as Predictive Biomarkers for Chemotherapy Response. Children’s Oncology Group; Cherry, Mohamad. (405) 271-8777


AREN14B1-Q: Analysis of 1q Gain in Subsets of Favorable Histology Wilms Tumor. Children’s Oncology Group; Mullen, Elizabeth Anne. (617) 632-1938

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